Ketogenic Diet is a dietary composition that aims to change the metabolic conditions of Glucose (sugar / carbohydrates) into metabolism of Fat (ketogenesis). Where the body will use Fat as the main fuel for metabolism, and no longer use Glucose / Carbohydrates (Glycolysis – Oxidative Phosphorylation).
This dietary composition will make the fat cells in the body processed / converted into energy sources (lipolysis) in the form of “Free Fatty Acid (FFA)” and “Ketone Bodies (Ketones)”. Because the metabolism of this Fat requires a process of Respiration (high oxygen) to produce energy from FFA and Ketones circulating in the body, only normal / healthy cells (perfect mithocondria) can use FFA and Ketone as a source of energy for metabolism (Beta-Oxidation)
Thus abnormal cells such as cancer cells, infected cells (viruses), damaged / aging cells, and pathogens (the bacteria, parasites, fungi / fungi) will lose their main energy source Glucose, and will be eliminated with this Ketogenic Diet
For cancer cells (CA) and infected cells (virus / pathogen), Glucose metabolism (Glycolysis) is the key to their ability to thrive. Without a sufficient source of Glucose, they will experience starvation and in some types of cancer cells can switch to the source of Glutamine (glutaminolysis) to obtain a replacement energy source as a metabolism fuel (Glutaminolysis). In this Ketogenic Diet application for patients with Cancer or Virus / Pathogen Infections, it should also limit the amount of protein intake (max 0.8g – 1.2g per kg of dry muscle mass / lean body mass). The suggested protein source is a low protein source of Glutamine such as fish.
Cancer cells are cells that have a defect in their cell Mithocondria
Cancer cells are cells that have a defect in their cell Mithocondria, so the cell can not use Fat (ketones) for its metabolism. This is a fundamental fundamental of all types of malignant cells (cancer), which can only use glucose and ferment to produce lactic acid, in low or high oxygen conditions (Wikipedia – Warburg Effect)
It is also the basis for detecting the location of cancer cells in the medical world, as in the diagnosis through PET SCAN using Glucose solution with Radioactive label (2-F-2-Deoxyanglucose / FDG), to see the accumulated location of the fluid in the body.
In i-KetoFast, Ketogenic Diet is a dietary composition that regulates what is eaten at mealtime after IF fasting. An example of a 16-hour IF fasting (8 pm to 12 noon the next day) means organizing what is eaten between 12 noon (lunch) until 7.30 pm (start dinner and stop at 8 pm).
Consumption of carbohydrates more than 50 grams / day, will automatically cancel ketosis (metabolism Fat) in progress.
In the common Ketogenic Diet (Universal) all Animal sources are allowed. this includes the Fat contained in the source of the Animal. And for vegetable sources, very limited can be consumed. Only limited to leafy vegetables (High Fiber / Fiber) and not starchy. For the selection of fruit is very limited type and a little amount of consumption per day, because the content of fruit sugar (fructose) that can trigger a rise in blood sugar levels faster than Glucose.
Always stick with the list of “Ketogenic Vegetables” and “Ketogenic Fruits” as a reference. Avoid all Vegetable sources outside of the list. On each list also has a maximum serving dose that may be consumed in 1 day. Consuming more than the maximum limit on the list will increase the risk of an increase in insulin hormone, which will cancel Ketosis (Fat metabolism) and give adverse effects to the previously consumed Fat intake.
* The above percentage ratio is calculated from the total daily calories and is converted to “gram” (Fat = 9 calories / g; Protein = 4 calories / g; Carbohydrates = 4 calories / g)
* For the cancer ketogenic / infectious diet method, the selection of protein sources is limited to low-glutamine protein sources such as fish, seafood and poultry.